The 26-year-old, raised in the UK but born in California, will begin work on the new movie in December.
His previous credits include last year’s The Imaginarium of Dr Parnassus alongside the late Heath Ledger.
Former Spider-Man star Tobey Maguire and director Sam Raimi departed the franchise after making three films.
Full story: BBC News – British actor Andrew Garfield cast as new Spider-Man