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Best Nootropic Supplements to Take

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Nootropics, also referred to as smart drugs, are on the rise. And it comes as no surprise, as these compounds are able to do things such as boost concentration and focus. Not only that, many individuals that suffer from conditions such as depression or anxiety also often benefit from the use of these substances. But what are nootropics and how can you benefit from them?

What Are Nootropics?

Nootropics are a specific supplement that is meant to improve cognitive function. This ranges from being able to improve your attention span and focus all the way to memory enhancement and improved creativity, motivation, and more.

The etymology of the word nootropic literally translates from the Greek words νόος and τροπή to mean a turning of the mind. 

Types of Nootropics

Nootropics come in several variations. From naturally occurring compounds to the synthetic varieties. They all have a use and the ability to aid in learning, understanding, and overall improved cognitive functions. 


One of the more commonly heard of nootropics is caffeine. Yes, it is true, caffeine is indeed a nootropic compound and a strong one at that. 

Caffeine can be found in several areas and is often considered a central nervous system stimulant. In other words, it has the ability to increase activity in your central nervous system. 

Often we as a society understand that caffeine is readily available in some of our favorite goodies. Some of these goodies include teas, coffees, and energy drinks. And while it is one of the most highly consumed psychoactive drugs, it is actually not regulated. 

The fact that it is an unregulated substance easily makes it something on both the good and bad spectrum. For example, it is true that caffeine can work to improve cognitive function. If used in excess, it can also cause anxiety, problems with sleep, and even become addictive. In other words, the more you consume the more your body builds a tolerance. Leading to more intake over time. 

The good news is that you can detox yourself from caffeine use and in some cases reduce the intake substantially. 

Synthetic Nootropics

While nootropics are sometimes naturally occurring, more and more science is realizing that synthetic variations can be created and used as treatments for everything from dementia to depression and anxiety. Five of the more commonly used nootropic supplements include phenibut, alpha GPC, the NMN supplement, noopept, and phenylpiracetam. 


Phenibut is one of the older and more thoroughly tested nootropics. It helps with cognitive function. However, it also transcends the basic cognitive functions and also aids with anxiety. It is a GABA analogue meaning that it affects GABA, a primary inhibitory transmitter for mammals. Phenibut works to reduce excitability in the nervous system. In doing so it reduces the prevalence of anxiety in its users.  

Alpha GPC 

Alpha GPC is a choline compound. In most cases, this compound can be found naturally within the brain. However, there have been studies to show that choline tends to fluctuate. If it fluctuates too much it can cause illnesses such as non-alcoholic fatty liver disease or even cause muscle damage. When taking Alpha GPC, choline levels are boosted, ensuring that the illnesses aforementioned do not occur.

NMN supplement

NMN is a nucleotide that is derived from nicotinamide and ribose. It’s commonly found in the brain and is typically created by B vitamins. Rather than just affecting general cognitive functions, the NMN supplement is capable of reducing signs of aging in the brain as well as increasing both muscle and strength in its users. 


Noopept is a smart drug that is also considered a prodrug. This means that the body can more easily absorb the substance. Noopept primarily aids acetylcholine and AMPA receptors. In aiding these receptors, noopept allows higher levels of acetylcholine in the body. Meaning that over time more and more complete messages transmit to muscles and memory. 


Phenylpiracetam is of the racetam family of nootropics. It was initially studied as a possible stress reliever and was found to be more neuroprotective than its cousin piracetam. The primary use of phenylpiracetam is as a psychostimulant. In other words, it makes you more alert while keeping you calm. Not only that, phenylpiracetam can improve memory recall and memory storage as well.  

Nootropics, or smart drugs have the ability to help many individuals meet or exceed their goals. This makes them some of the most sought after supplements on the market. Getting to know your needs and what nootropic matches them the best is the first step of identifying the perfect nootropic for you.

These statements have not been evaluated by the Food and Drug Administration. The products listed in this article are not intended to diagnose, treat, cure, or prevent any disease.

Members of the editorial and news staff of the Daily Caller were not involved in the creation of this content.