The U.S. Food and Drug Administration says makers of combination prescription medications can include no more than 325 mg of acetaminophen in each tablet or capsule.
The decision to restrict acetaminophen content was driven by the risk of liver toxicity from the products, which account for about 200 million prescriptions in the U.S. each year, the FDA said a press briefing.
To that end, manufacturers of Rx products containing acetaminophen — usually opioids like codeine, oxycodone, and hydrocodone — will be required to include a boxed warning on the risk of severe liver injury in product labeling.
Full story: FDA Sets Limit on Acetaminophen in Combo Pain Meds
