The U.S. conducted a second round of retaliatory airstrikes at facilities used by Iran’s elite military and Iran-backed groups in Syria on Wednesday, Secretary of Defense Lloyd Austin said in a statement.

Attacks by Iranian-backed militias on bases in Iraq and Syria hosting U.S. troops numbered 41 on Wednesday after at least one more was confirmed, Fox News reported. The retaliatory strikes marked the second time the U.S. has targeted facilities linked to Iran and its proxy militias since the wave of attempted drone and rocket attacks beginning on Oct. 17.

“This precision self-defense strike is a response to a series of attacks against U.S. personnel in Iraq and Syria by IRGC-Quds Force affiliates,” Austin said in the statement. “The President has no higher priority than the safety of U.S. personnel, and he directed today’s action to make clear that the United States will defend itself, its personnel, and its interests.” (RELATED: Iran Using Group Behind Attacks On US Troops In The Middle East To Increase Pressure On White House)

President Joe Biden directed the attacks in eastern Syria on weapons storage facilities used by Iran’s Islamic Revolutionary Guard Corps (IRGC) and affiliated militias, the statement said. Two U.S. F-15 fighter jets conducted the airstrikes.

“The United States is fully prepared to take further necessary measures to protect our people and our facilities. We urge against any escalation. U.S. personnel will continue to conduct counter-ISIS missions in Iraq and Syria,” he added.

Following a series of attacks against U.S. persons in Iraq and Syria, U.S. Central Command (USCENTCOM) forces conducted an air strike against a facility in Syria used by Iran’s Islamic Revolutionary Guard Corps (IRGC) and affiliated groups. We will take all necessary measures to… pic.twitter.com/KoLGWbnaxo

— U.S. Central Command (@CENTCOM) November 8, 2023

“We are minimizing what these groups are able to use. We believe and we feel that these are proportionate responses,” Pentagon deputy press secretary Sabrina Singh said at a briefing Thursday afternoon. The Pentagon saw several secondary explosions after the initial strikes on the weapons storage building “as we expected,” she added.

The strikes “convey a clear message to Iran that we hold it accountable for attacks on U.S. forces and that we expect Iran to direct its proxies to stop,” she said.

Pentagon press secretary Brig. Gen. Pat Ryder on Monday characterized the operations as repeated “harassing attacks of drones and rockets.” At least 46 personnel sustained injuries including traumatic brain injuries and minor wounds from shrapnel, headaches, perforated ear drums and other conditions, he said.

All content created by the Daily Caller News Foundation, an independent and nonpartisan newswire service, is available without charge to any legitimate news publisher that can provide a large audience. All republished articles must include our logo, our reporter’s byline and their DCNF affiliation. For any questions about our guidelines or partnering with us, please contact licensing@dailycallernewsfoundation.org.